Iridium and palladium catalyst development

Project summary

This project is a three-stage collaborative programme of research between the Universities of Edinburgh and Strathclyde, combining complementary expertise in theoretical, preparative, and mechanistic organometallic chemistry to deliver new technologies for widespread application in preparative processes of direct relevance to the pharmaceutical, agrochemical, and fine chemical industries.

Specifically, theoretical modelling and practical applications of valuable N- heterocyclic carbene (NHC)-phosphine bidentate ligands are described. Further, supply of deuterium labelled compounds for the development of novel reaction monitoring techniques is also proposed. Finally, the use of non-coordinating counter ion methods for the development of environmentally-benign palladium and iridium catalysis is delineated.